Archaeological Site of Panamá Viejo and Historic District of Panamá
A Spanish colonial city: the first permanent European settlement in the Western Hemisphere.

Fortifications on the Caribbean Side of Panama: Portobelo-San Lorenzo (on the endangered list)
Ruins of Spanish colonial-era fortifications extending along the Caribbean coastline of Panama.

Coiba National Park and its Special Zone of Marine Protection

Darien National Park

Talamanca Range-La Amistad Reserves / La Amistad National Park *